Recently the U.S. Environmental Protection Agency (EPA) and commercial organizations have been transitioning towards using CARES NG (Cumulative and Aggregate Risk Evaluation System, Next Generation) software for their pesticide risk assessments.
Estimation of dietary exposures to pesticide residues in agricultural and livestock commodities is critical in regulating the safe use of pesticide products. The EPA and commercial organizations have long used the Dietary Exposure Evaluation Model-Food Commodity Intake Database (DEEM-FCID or DEEM) successfully for such purposes. However, there is no current plan to upgrade or maintain DEEM beyond the current version (DEEM 4.02) which is based on outdated 2005-2010 NHANES/WWEIA food consumption survey data.
The DEEM-FCID alternative.
An alternative cloud-based model, the Cumulative and Aggregate Risk Evaluation System-Next Generation (CARES NG), is being developed by Creme Global with the support of the non-profit CARES NG organization. CARES NG, is a cloud-based probabilistic model that is built upon public data and used to estimate aggregate and cumulative exposure to pesticides.
CARES-NG is now the recommended tool to estimate these exposures due to its enhanced functionality. Commercial organizations are now using it to evaluate new active ingredients for regulatory review and market launch.
Evaluate aggregate and cumulative risks.
CARES NG evaluates both aggregate and cumulative risks, meaning it looks at exposure to multiple pesticides across different routes (dietary, residential, etc.) and considers combined exposures for individuals and populations.
Enhanced features: CARES NG is able to model exposures from food, water, and other non-dietary sources. It also incorporates updated consumption data and improved analytical capabilities, making it a more comprehensive tool for cumulative risk assessments.
CARES NG is increasingly used by the EPA for more complex, multi-pathway risk assessments that need to account for cumulative exposure to multiple pesticides across various sources.
Download our publication and case study:
Use of CARES NG instead of DEEM-FCID to Conduct a Cumulative Dietary Exposure Assessment for Chlorotriazine Compounds.
