Aggregate exposure modelling of vitamin A from cosmetic products, diet and food supplements

Realism is important in estimating consumer exposure to a substance, especially when accounting for exposure from multiple sources. Humans are exposed to vitamin A from food, dietary supplements and cosmetics products. A probabilistic aggregate exposure model was developed for estimating exposure distributions to vitamin A (as retinol equivalents) in pre-/post-menopausal, and…

Authors: Tozer, S & Cian O’Mahony, Jen Hannah, John O’Brien, Seamus Kelly, Kirstin Kosemund-Meynen, Camilla Alexander-White

Publication date: 31/05/2019

All Publications, Exposure, Food Safety, Nutrition

ECETOC Technical Report no.126: Guidance for effective use of human exposure data in risk assessment of chemicals

This report details much of the current state-of-the-art of consumer exposure assessment data and models that can be used in chemical risk assessment, with a particular focus upon aggregate exposure assessment. Aggregate exposure considers all sources of exposure to a single chemical (e.g. hair care products, cosmetics, detergents, foods,…

Authors: O’Mahony C. et al on behalf of the ECETOC Task Force on guidance for effective use of human exposure data in risk assessment of chemicals

Publication date: 01/11/2016

All Publications, Chemicals, Exposure

Combining databases to estimate population exposure to cosmetics and personal care products

Authors: Comiskey Damien & Cian O’Mahony, E.J. Daly, Cronan McNamara

Publication date: 10/09/2014

All Publications, Chemicals, Exposure, Personal Care, Technology

Exposure to cosmetic products in Europe

Authors: Hall Barbara, Sarah Tozer, Bob Safford, Manuela Coroama, Winfried Steiling, Marie-Cristine Leneveu-Duchemin, Cronan McNamara, Michael Gibney

Publication date: 05/09/2007

All Publications, Chemicals, Exposure, Personal Care

Probabilistic Aggregate Exposure Modelling for a Broad Spectrum Antimicrobial in Personal Cleansing Products

Realistic estimates of chemical aggregate exposure are needed to ensure consumer safety and satisfy the requirements of regulators. In most cases, aggregate exposure is estimated simply by adding deterministic exposures from all product types containing the chemical. However, this summation will result in an unrealistically-conservative estimate since individuals vary…

Authors: Tozer Sarah, J F Nash, and E.J. Daly

Publication date: 01/09/2013

All Publications, Chemicals, Exposure, Personal Care

Probabilistic aggregate exposure modelling to aluminium from the diet, cosmetics and medicines

Authors: Tozer Sarah, Cian O’Mahony, Jay Nash, Seamus Kelly, E.J. Daly

Publication date: 10/09/2014

All Publications, Chemicals, Exposure, Food Safety, Nutrition, Personal Care

Critical and systematic evaluation of data for estimating human exposures to 2,4-dichlorophenoxyacetic acid (2,4-D) – quality and generalizability

The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) has been commercially available since the 1940’s. Despite decades of data on 2,4-D in food, air, soil, and water, as well as in humans, the quality the quality of these data has not been comprehensively evaluated. Using selected elements of the Biomonitoring, Environmental Epidemiology,…

Authors: LaKind Judy S. & Carol J. Burns, Daniel Q. Naiman, Cian O’Mahony, Giulia Vilone, Annette J. Burns & Joshua S. Naiman

Publication date: 20/11/2017

All Publications, Chemicals, Exposure

A framework to determine the effectiveness of dietary exposure mitigation to chemical contaminants

In order to ensure the food safety, risk managers may implement measures to reduce human exposure to contaminants via food consumption. The evaluation of the effect of a measure is often an overlooked step in risk analysis process. The aim of this study was to develop a systematic approach…

Authors: van der Fels-Klerx, H.J. (Ine) & Simon G. Edwards, Marc C. Kennedy, Sue O’Hagan, Cian O’Mahony, Gabriele Scholz, Pablo Steinberg, Alessandro Chiodini

Publication date: 01/12/2014

All Publications, Chemicals, Exposure, Food Safety

Aggregate exposure to vitamin A from cosmetics and the diet

Authors: Tozer S, Kosemund K, Kelly S, O’Mahony C.

Publication date: 16/10/2015

All Publications, Chemicals, Exposure, Food Safety, Nutrition

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